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Subtelomeric silencing of the MTL3 locus of Candida glabrata requires yKu70, yKu80, and Rif1 proteins
(2010-10)
"Candida glabrata is a haploid opportunistic fungal pathogen that is phylogenetically related to Saccharomyces cerevisiae. Even though C. glabrata has no known sexual cycle, it contains, like S. cerevisiae, three mating ...
Genotyping of the MTL loci and susceptibility to two antifungal agents of Candida glabrata clinical isolates
(2009-08)
"The opportunistic fungal pathogen Candida glabrata is the second most common isolate from bloodstream infections worldwide and is naturally less susceptible to the antifungal drug fluconazole than other Candida species. ...
High resistance to oxidative stress in the fungal pathogen Candida glabrata is mediated by a single catalase, Cta1p, and is controlled by the transcription factors Yap1p, Skn7p, Msn2p, and Msn4p
(2008-05)
"We characterized the oxidative stress response of Candida glabrata to better understand the virulence of this fungal pathogen. C. glabrata could withstand higher concentrations of H2O2 than Saccharomyces cerevisiae and ...
yKu70/yKu80 and Rif1 regulate silencing differentially at telomeres in Candida glabrata
(2008-12)
"Candida glabrata, a common opportunistic fungal pathogen, adheres efficiently to mammalian epithelial cells in culture. This interaction in vitro depends mainly on the adhesin Epa1, one of a large family of cell wall ...
Occurrence of killer Candida glabrata clinical isolates
(2012)
"In this work we characterized the occurrence of killer activity in 64 Candida glabrata clinical isolates under different conditions. We found that only 6.25 % of the clinical isolates tested were positive for killer ...
Oxidative stress response to menadione and cumene hydroperoxide in the opportunistic fungal pathogen Candida glabrata
(2009-07)
"Candida glabrata is an opportunistic fungal pathogen that can cause severe invasive infections and can evade phagocytic cell clearance. We are interested in understanding the virulence of this fungal pathogen, in particular ...
Candida glabrata encodes a longer variant of the mating type (MAT) alpha2 gene in the mating type-like MTL3 locus, which can form homodimers
(Oxford University Press, 2016)
"The fungal pathogen Candida glabrata is a haploid asexual yeast. Candida glabrata contains orthologs of the genes that control mating and cell-type identity in other fungi, which encode putative transcription factors ...
Chromatin loop formation induced by a subtelomeric protosilencer represses EPA genes in Candida glabrata
(Genetics Society of America, 2018)
"Adherence, an important virulence factor, is mediated by the EPA (Epithelial Adhesin) genes in the opportunistic pathogen Candida glabrata. Expression of adhesin-encoding genes requires tight regulation to respond to harsh ...
Molecular characterization of the silencing complex SIR in Candida glabrata hyperadherent clinical isolates
(Elsevier, 2018)
"An important virulence factor for the fungal pathogen Candida glabrata is the ability to adhere to the host cells, which is mediated by the expression of adhesins. Epa1 is responsible for ?95% of the in vitro adherence ...
Analysis of volatile molecules present in the secretome of the fungal pathogen Candida Glabrata
(MDPI, 2021)
"Candida albicans, Candida glabrata, Candida parapsilosis and Candida tropicalis are the four most common human fungal pathogens isolated that can cause superficial and invasive infections. It has been shown that specific ...