Browsing División de Biología Molecular by Subject "Valproic acid"

Now showing items 1-2 of 2

    • 5-Aza-2?-Deoxycytidine and Valproic Acid in Combination with CHIR99021 and A83-01 Induce Pluripotency Genes Expression in Human Adult Somatic Cells 

      Aguirre Vazquez, Alain Jesús; Salazar Olivo, Luis Antonio; Flores Ponce, Xóchitl Natalia; Arriaga Guerrero, Ana Leticia; Garza Rodríguez, Dariela; Camacho Moll, María Elena; Velasco, Iván; Castorena Torres, Fabiola; Dadheech, Nidheesh; Bermúdez de León, Mario Abelardo (MDPI, 2021)
      "A generation of induced pluripotent stem cells (iPSC) by ectopic expression of OCT4, SOX2, KLF4, and c-MYC has established promising opportunities for stem cell research, drug discovery, and disease modeling. While this ...

    • Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine 

      Aguirre Vazquez, Alain Jesús; Castorena Torres, Fabiola; Silva Ramírez, Beatriz; Peñuelas Urquides, Katia; Camacho Moll, María Elena; Salazar Olivo, Luis Antonio; Velasco, Iván; Bermúdez de León, Mario Abelardo (Springer Nature, 2023)
      Background The generation of induced pluripotent stem cells has opened the field of study for stem cell research, disease modeling and drug development. However, the epigenetic signatures present in somatic cells make cell ...