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Occurrence of killer Candida glabrata clinical isolates

dc.contributor.authorArroyo Helguera, Omar Elind
dc.contributor.authorDe Las Peñas Nava, Alejandro
dc.contributor.authorCastaño Navarro, Irene Beatriz
dc.contributor.editorSociedade Brasileira de Microbiologia
dc.identifier.citationO, Arroyo-Helguera, Alejandro, De Las Penas, & Irene, Castaño. (2012). Occurrence of killer Candida glabrata clinical isolates. Brazilian Journal of Microbiology, 43(3), 880-887.
dc.description.abstract"In this work we characterized the occurrence of killer activity in 64 Candida glabrata clinical isolates under different conditions. We found that only 6.25 % of the clinical isolates tested were positive for killer activity against a Saccharomyces cerevisiae W303 sensitive strain. Sensitivity of killer activity to different values of pH and temperatures was analyzed. We found that the killer activity presented by all isolates was resistant to every pH and temperature tested, although optimal activity was found at a range of pH values from 4 to 7 and at 37ºC. We did not observe extrachromosomal genetic elements associated with killer activity in any of the positive C. glabrata isolates. The killer effect was due to a decrease in viability and DNA fragmentation in sensitive yeast."
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.subjectCandida glabrata
dc.subjectKiller activity
dc.titleOccurrence of killer Candida glabrata clinical isolates
dc.rights.accessAcceso Abierto

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional