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Utility of curcumin for the treatment of diabetes mellitus: Evidence from preclinical and clinical studies

dc.contributor.authorRivera Mancía, Susana Yesenia
dc.contributor.authorTrujillo Silva, Daniela Joyce
dc.contributor.authorPedraza Chaverri José
dc.contributor.editorElsevier
dc.date.accessioned2018-12-13T21:09:25Z
dc.date.available2018-12-13T21:09:25Z
dc.date.issued2018
dc.identifier.citationSusana Rivera-Mancía, Joyce Trujillo, José Pedraza Chaverri, Utility of curcumin for the treatment of diabetes mellitus: Evidence from preclinical and clinical studies, Journal of Nutrition & Intermediary Metabolism, Volume 14, 2018, Pages 29-41.
dc.identifier.urihttp://hdl.handle.net/11627/4821
dc.description.abstract"Turmeric or Curcuma longa is a natural product, whose medicinal properties have been extensively studied and a wide variety of therapeutic effects on several diseases such as neurodegenerative, hepatic and renal damage, cancer, and diabetes have been mainly attributed to its curcuminoid content. In the last decades, diabetes mellitus has become an alarming worldwide health issue, because of the increasing number of people suffering from the disease, as well as the devastating consequences for them. In this paper, we review the current basic and clinical evidence about the potential of curcumin/curcuminoids for the treatment of diabetes mellitus, mainly by its hypoglycemic, antioxidant, and anti-inflammatory properties. The activity of curcumin (or curcuminoids) as a hypoglycemic agent or just as an adjuvant to improve the metabolic profile and to ameliorate the associated complications of diabetes mellitus, such as diabetic nephropathy and cardiopathy is discussed. The interactions between curcumin and conventional antidiabetic drugs might be explored for the therapeutic management of diabetes mellitus."
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectDiabetes mellitus
dc.subjectCurcumin
dc.subjectGlucose
dc.subjectLipids
dc.subject.classificationFARMACOLOGÍA
dc.titleUtility of curcumin for the treatment of diabetes mellitus: Evidence from preclinical and clinical studies
dc.typearticle
dc.identifier.doihttps://doi.org/10.1016/j.jnim.2018.05.001
dc.rights.accessAcceso Abierto


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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