Show simple item record

Title

A Lineage of Begomoviruses Encode Rep and AC4 Proteins of Enigmatic Ancestry: Hints on the Evolution of Geminiviruses in the New World

dc.contributor.authorTorres Herrera, Sandra Iliana
dc.contributor.authorRomero Osorio, Angélica
dc.contributor.authorMoreno Valenzuela, Oscar
dc.contributor.authorPastor Palacios, Guillermo
dc.contributor.authorCardenas Conejo, Yair
dc.contributor.authorRamírez Prado, Jorge H.
dc.contributor.authorRiego Ruíz, Lina Raquel
dc.contributor.authorMinero García, Yereni
dc.contributor.authorAmbriz Granados, Salvador
dc.contributor.authorArgüello Astorga, Gerardo Rafael
dc.date.accessioned2020-03-04T00:53:25Z
dc.date.available2020-03-04T00:53:25Z
dc.date.issued2019
dc.identifier.citationTorres-Herrera, S.I.; Romero-Osorio, A.; Moreno-Valenzuela, O.; Pastor-Palacios, G.; Cardenas-Conejo, Y.; Ramírez-Prado, J.H.; Riego-Ruiz, L.; Minero-García, Y.; Ambriz-Granados, S.; Argüllo-Astorga, G.R. A Lineage of Begomoviruses Encode Rep and AC4 Proteins of Enigmatic Ancestry: Hints on the Evolution of Geminiviruses in the New World. Viruses 2019, 11, 644.
dc.identifier.urihttp://hdl.handle.net/11627/5291
dc.description.abstract"The begomoviruses (BGVs) are plant pathogens that evolved in the Old World during the Cretaceous and arrived to the New World (NW) in the Cenozoic era. A subgroup of NW BGVs, the "Squash leaf curl virus (SLCV) lineage" (S-Lin), includes viruses with unique characteristics. To get clues on the evolutionary origin of this lineage, a search for divergent members was undertaken. Four novel BGVs were characterized, including one that is basal to the group. Comparative analyses led to discover a ~670 bp genome module that is nearly exclusive of this lineage, encompassing the replication origin, the AC4 gene, and 480 bp of the Rep gene. A similar DNA module was found in two curtoviruses, hence suggesting that the S-Lin ancestor acquired its distinctive genomic segment by recombination with a curtovirus. This hypothesis was definitely disproved by an in-depth sequence analysis. The search for homologs of S-Lin Rep uncover the common origin of Rep proteins encoded by diverse Geminiviridae genera and viral "fossils" integrated at plant genomes. In contrast, no homolog of S-Lin Rep was found in public databases. Consequently, it was concluded that the SLCV clade ancestor evolved by a recombination event between a primitive NW BGV and a virus from a hitherto unknown lineage."
dc.publisherMDPI AG
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectGeminivirus evolution
dc.subjectReplication protein
dc.subjectCurtovirus taxonomy
dc.subjectEndogenous viral element
dc.subjectReplication origin
dc.subjectRolling-circle replication
dc.subject.classificationVIROLOGÍA
dc.titleA Lineage of Begomoviruses Encode Rep and AC4 Proteins of Enigmatic Ancestry: Hints on the Evolution of Geminiviruses in the New World
dc.typearticle
dc.identifier.doihttps://doi.org/10.3390/v11070644
dc.rights.accessAcceso Abierto


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional