Browsing Publicaciones Científicas Biología Molecular by Author "5e404d01-d06d-450c-b29c-d6242d3d6cbf"

Now showing items 1-4 of 4

    • Advances in the Properties of Incomptine A: Cytotoxic Activity and Downregulation of Hexokinase II in Breast Cancer Cell Lines 

      Arietta García, Angel Giovanni; Calzada, Fernando; Ramírez Sánchez, Israel; Bautista Redonda, Francisco Elihú; García Hernández, Normand; Ordoñez Razo, Rosa María (MDPI, 2023)
      Breast cancer treatments are limited by the cancer subtype and its selectivity towards tumor cells, hence the importance of finding compounds that increase the survival of healthy cells and target any subtype. Incomptine ...

    • Expanding the Study of the Cytotoxicity of Incomptines A and B against Leukemia Cells 

      Calzada, Fernando; García Hernández, Normand; Hidalgo Figueroa, Sergio Nemorio; Bautista Redonda, Francisco Elihú; Barbosa Cabrera, Elizabeth; Velázquez González, Claudia; Hernández Caballero, Marta Elena (MDPI, 2022)
      "Heliangolide-type sesquiterpene lactones (HTSLs) are phytocompounds with several pharmacological activities including cytotoxic and antitumor activity. Both bioactivities are related to an ?-methylene-?-lactone moiety and ...

    • Linearolactone Induces Necrotic-like Death in Giardia intestinalis Trophozoites: Prediction of a Likely Target 

      Argüello García, Raúl; Calzada, Fernando; Chávez Munguía, Bibiana; Matus Meza, Audifás Salvador; Bautista Redonda, Francisco Elihú; Barbosa Cabrera, Reyna Elizabeth; Velázquez, Claudia; Hernández Caballero, Marta Elena; Ordoñez Razo, Rosa Maria; Velázquez Domínguez, José Antonio (MDPI, 2022)
      "Linearolactone (LL) is a neo-clerodane type diterpene that has been shown to exert giardicidal effects; however, its mechanism of action is unknown. This work analyzes the cytotoxic effect of LL on Giardia intestinalis ...

    • Understanding the Anti-Diarrhoeal Properties of Incomptines A and B: Antibacterial Activity against Vibrio cholerae and Its Enterotoxin Inhibition 

      Calzada, Fernando; Bautista Redonda, Francisco Elihú; Hidalgo Figueroa, Sergio Nemorio; García Hernández, Normand; Velázquez, Claudia; Barbosa Cabrera, Reyna Elizabeth; Valdes Guevara, Miguel Andrés; Solares Pascasio, Jesús Iván (MDPI, 2022)
      "Incomptines A (IA) and B (IB) are two sesquiterpene lactones with antiprotozoal, antibacterial, cytotoxic, antitumor, spermicidal, and phytotoxic properties. The antibacterial activity of IA and IB against bacteria causing ...