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Effects of nitrogen-doped multiwall carbon nanotubes on murine fibroblasts

dc.contributor.authorMunguía López, Jose Gil
dc.contributor.authorMuñoz Sandoval, Emilio
dc.contributor.authorOrtiz Medina, Josue
dc.contributor.authorRodríguez Macías, Fernando Jaime
dc.contributor.authorDe León Rodríguez, Antonio
dc.contributor.editorHindawi Publishing Corporation
dc.date.accessioned2018-03-23T23:59:40Z
dc.date.available2018-03-23T23:59:40Z
dc.date.issued2015
dc.identifier.citationJ. G. Munguía-Lopez, E. Muñoz-Sandoval, J. Ortiz-Medina, F. J. Rodriguez-Macias, and A. De Leon-Rodriguez, “Effects of Nitrogen-Doped Multiwall Carbon Nanotubes on Murine Fibroblasts,” Journal of Nanomaterials, vol. 2015, Article ID 801606, 7 pages, 2015. doi:10.1155/2015/801606
dc.identifier.urihttp://hdl.handle.net/11627/3704
dc.description.abstract"The effect of nitrogen-doped multiwall carbon nanotubes (CNx) on the proliferation of NIH-3T3murine fibroblasts is presented. CNTs were dispersed in distillated water and incubated with mammalian cells in order to evaluate their toxicity. Also, the influence of factors such as dosage (7 and 70 mu g/mL), exposure time (24 to 96 h), and the exposure route (before and after cell liftoff) on the cell proliferation was evaluated. When the CNx were simultaneously incubated with the cells, the control culture reached a maximum cell concentration of 1.3 x 10(5) +/- 3.4 x 10(4) cells per well at 96 h, whereas cultures with 7 mu g/mL reached a concentration of 2.6 x 10(4) +/- 5.3 x 10(3) cells. In the case of 70 mu g/mL of CNx most of the cells were dead. The CNx that were added 24 h after cell dissociation showed that live cells decreased, with a cell concentration of 9.6 x 10(4) +/- 9 x 10(3) for 7 mu g/mL and 5.5 x 10(4) +/- 9.5 x 10(3) for 70 mu g/mL, in contrast to control cultures with 1.1 x 10(6) +/- 1.5 x 10(4). The results showed that the CNx had cytotoxic effects depending on the concentration and exposure route."
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.classificationCIENCIAS TECNOLÓGICAS
dc.titleEffects of nitrogen-doped multiwall carbon nanotubes on murine fibroblasts
dc.typearticle
dc.identifier.doihttp://dx.doi.org/10.1155/2015/801606
dc.rights.accessAcceso Abierto


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional