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On suitable observables for the chaotic Peroxidase-Oxidase autocatalytic reaction

dc.contributor.authorMéndez González, José Martín
dc.contributor.authorFemat Flores, Alejandro Ricardo
dc.date.accessioned2019-08-27T22:27:29Z
dc.date.available2019-08-27T22:27:29Z
dc.date.issued2018
dc.identifier.citationJ.M. Méndez-González, R. Femat, On suitable observables for the chaotic Peroxidase-Oxidase autocatalytic reaction, IFAC-PapersOnLine, Volume 51, Issue 13, 2018, Pages 109-114.
dc.identifier.urihttp://hdl.handle.net/11627/5136
dc.description.abstract"Neurodegenerative diseases such as Alzheimer’s and Parkinson present oxidative damage of neurocytes generally caused by reactive oxygen species (ROS). Heme peroxidases consume and produce ROS thus serving as suppresors and promoters of ROS-related pathology A core reaction network of production and consumption of hydrogen peroxide and superoxide is the Peroxidase-Oxidase (PO). PO reaction was among the first biochemical oscillators to be experimentally and numerically studied, with dynamical scenarios such as multiple steady states, complex oscillations and chaos. In particular, the oxyferrous peroxidase (compound III) and O2 have been used as observable variables in experiments to record the chaotic dynamics. Moreover, PO reaction has been embedded in nanoparticles in order to serve as a sensor for ROS. In this contribution we quantified, using observability coefficients, which chemical species is more suitable to observe and reconstruct the characteristic complex dynamics of the PO reaction."
dc.publisherInternational Federation of Automatic Control
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectChaotic behaviour
dc.subjectObservability indices
dc.subjectReactive oxygen species
dc.subjectNeurodegenerative diseases
dc.subjectAutocatalysis
dc.subject.classificationMATEMÁTICAS
dc.titleOn suitable observables for the chaotic Peroxidase-Oxidase autocatalytic reaction
dc.typearticle
dc.identifier.doihttps://doi.org/10.1016/j.ifacol.2018.07.263
dc.rights.accessAcceso Abierto


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional