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Self-tuning insulin adjustment algorithm for type 1 diabetic patients based on multi-doses regime

dc.contributor.authorCampos Delgado, Daniel Ulises
dc.contributor.authorFemat Flores, Alejandro Ricardo
dc.contributor.authorHernández Ordoñez, Martín
dc.contributor.authorGordillo Moscoso, Antonio Augusto
dc.date.accessioned2018-07-11T18:30:06Z
dc.date.available2018-07-11T18:30:06Z
dc.date.issued2005
dc.identifier.citationD. U. Campos-Delgado, R. Femat, M. Hernández-Ordoñez, and A. Gordillo-Moscoso, “Self-Tuning Insulin Adjustment Algorithm for Type 1 Diabetic Patients based on Multi-Doses Regime,” Applied Bionics and Biomechanics, vol. 2, no. 2, pp. 61-71, 2005. https://doi.org/10.1533/abbi.2004.0031.
dc.identifier.urihttp://hdl.handle.net/11627/4041
dc.description.abstract"A self-tuning algorithm is presented for on-line insulin dosage adjustment in type 1 diabetic patients (chronic stage). The algorithm suggested does not need information of the patient insulin–glucose dynamics (model-free). Three doses are programmed daily, where a combination of two types of insulin: rapid/short and intermediate/long acting is injected into the patient through a subcutaneous route. The doses adaptation is performed by reducing the error in the blood glucose level from euglycemics. In this way, a total of five doses are tuned per day: three rapid/short and two intermediate/long, where there is large penalty to avoid hypoglycemic scenarios. Closed-loop simulation results are illustrated using a detailed nonlinear model of the subcutaneous insulin–glucose dynamics in a type 1 diabetic patient with meal intake."
dc.publisherHindawi
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.classificationMATEMÁTICAS
dc.titleSelf-tuning insulin adjustment algorithm for type 1 diabetic patients based on multi-doses regime
dc.typearticle
dc.identifier.doihttp://dx.doi.org/10.1533/abbi.2004.0031
dc.rights.accessAcceso Abierto


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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