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A Review of the Ephedra genus: Distribution, Ecology, Ethnobotany, Phytochemistry and Pharmacological Properties

dc.contributor.authorGonzález Juárez, Daphne Edith
dc.contributor.authorEscobedo-Moratilla, Abraham
dc.contributor.authorFlores Rivas, Joel David
dc.contributor.authorHidalgo Figueroa, Sergio Nemorio
dc.contributor.authorMartínez Tagüeña, Natalia
dc.contributor.authorMorales Jiménez, Jesús Israel
dc.contributor.authorMuñiz Ramirez, Alethia
dc.contributor.authorPastor Palacios, Guillermo
dc.contributor.authorPérez Miranda, Sandra
dc.contributor.authorRamírez Hernández, Alfredo
dc.contributor.authorTrujillo Silva, Daniela Joyce
dc.contributor.authorBautista Redonda, Francisco Elihú
dc.date.accessioned2021-04-26T19:14:07Z
dc.date.available2021-04-26T19:14:07Z
dc.date.issued2020
dc.identifier.citationGonzález-Juárez, D.E.; Escobedo-Moratilla, A.; Flores, J.; Hidalgo-Figueroa, S.; Martínez-Tagüeña, N.; Morales-Jiménez, J.; Muñiz-Ramírez, A.; Pastor-Palacios, G.; Pérez-Miranda, S.; Ramírez-Hernández, A.; Trujillo, J.; Bautista, E. A Review of the Ephedra genus: Distribution, Ecology, Ethnobotany, Phytochemistry and Pharmacological Properties. Molecules 2020, 25, 3283. https://doi.org/10.3390/molecules25143283
dc.identifier.urihttp://hdl.handle.net/11627/5593
dc.description.abstract"Ephedra is one of the largest genera of the Ephedraceae family, which is distributed in arid and semiarid regions of the world. In the traditional medicine from several countries some species from the genus are commonly used to treat asthma, cold, flu, chills, fever, headache, nasal congestion, and cough. The chemical constituents of Ephedra species have been of research interest for decades due to their contents of ephedrine-type alkaloids and its pharmacological properties. Other chemical constituents such as phenolic and amino acid derivatives also have resulted attractive and have provided evidence-based supporting of the ethnomedical uses of the Ephedra species. In recent years, research has been expanded to explore the endophytic fungal diversity associated to Ephedra species, as well as, the chemical constituents derived from these fungi and their pharmacological bioprospecting. Two additional aspects that illustrate the chemical diversity of Ephedra genus are the chemotaxonomy approaches and the use of ephedrine-type alkaloids as building blocks in organic synthesis. American Ephedra species, especially those that exist in Mexico, are considered to lack ephedrine type alkaloids. In this sense, the phytochemical study of Mexican Ephedra species is a promising area of research to corroborate their ephedrine-type alkaloids content and, in turn, discover new chemical compounds with potential biological activity. Therefore, the present review represents a key compilation of all the relevant information for the Ephedra genus, in particular the American species, the species distribution, their ecological interactions, its ethnobotany, its phytochemistry and their pharmacological activities and toxicities, in order to promote clear directions for future research."
dc.publisherMDPI
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEndophytic fungi
dc.subjectEphedra species
dc.subjectEphedrine-type alkaloids
dc.subjectEthnobotany
dc.subjectPharmacology
dc.subjectSpecialized metabolites
dc.subjectToxicity
dc.subject.classificationBIOQUÍMICA
dc.titleA Review of the Ephedra genus: Distribution, Ecology, Ethnobotany, Phytochemistry and Pharmacological Properties
dc.typearticle
dc.identifier.doihttps://doi.org/10.3390/molecules25143283
dc.rights.accessAcceso Abierto


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional