Listar Publicaciones Científicas Biología Molecular por título
Mostrando ítems 373-392 de 584
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Improved Stability of Human CGI-58 Induced by Phosphomimetic S237E Mutation
(American Chemical Society, 2022)"In lipolysis, the activating function of CGI-58 is regulated by its interaction with perilipin 1 (PLIN1) localized on the lipid droplet (LD), and its release is controlled by phosphorylation. Once lipolysis is stimulated ... -
In Kluyveromyces lactis a Pair of Paralogous Isozymes Catalyze the First Committed Step of Leucine Biosynthesis in Either the Mitochondria or the Cytosol
(Frontiers Media S.A., 2020)"Divergence of paralogous pairs, resulting from gene duplication, plays an important role in the evolution of specialized or novel gene functions. Analysis of selected duplicated pairs has elucidated some of the mechanisms ... -
In vivo evidence for homo- and heterodimeric interactions of Arabidopsis thaliana dehydrins AtCOR47, AtERD10, and AtRAB18
(2017-12)"Dehydrins (DHNs) are intrinsically disordered proteins that play central roles in plant abiotic stress responses; however, how they work remains unclear. Herein, we report the in planta subcellular localization of Arabidopsis ... -
In Vivo Neuropharmacological Effects of Neophytadiene
(MDPI, 2023)Neophytadiene (NPT) is a diterpene found in the methanolic extracts of Crataeva nurvala and Blumea lacera, plants reported with anxiolytic-like activity, sedative properties, and antidepressant-like actions; however, the ... -
Inactivation of the transcription factor mig1 (YGL035C) in Saccharomyces cerevisiae improves tolerance towards monocarboxylic weak acids: acetic, formic and levulinic acid
(Springer, 2018)"Toxic concentrations of monocarboxylic weak acids present in lignocellulosic hydrolyzates affect cell integrity and fermentative performance of Saccharomyces cerevisiae. In this work, we report the deletion of the general ... -
Indole modifies the central carbon flux in the anaerobic metabolism of Escherichia coli: application to the production of hydrogen and other metabolites
(Elsevier, 2016-12)"Indole is a bicyclic signaling molecule with effects on both eukaryotic and prokaryotic cells. The majority of studies of indole action have been performed with bacteria cultured under aerobic conditions and little ... -
Insights on structure and function of a late embryogenesis abundant protein from Amaranthus cruentus: an intrinsically disordered protein involved in protection against desiccation, oxidant conditions, and osmotic stress
(Frontiers Media S.A., 2017-05)"Late embryogenesis abundant (LEA) proteins are part of a large protein family that protect other proteins from aggregation due to desiccation or osmotic stresses. Recently, the Amaranthus cruentus seed proteome was ... -
Interacciones funcionales entre los receptores nicotinicos y P2X en neuronas del ganglio celiaco de cobayo.
(2006)"En el ganglio celiaco, la liberación de la acetilcolina (ACh) y del ATP activan canales nicotínicos y P2X, respectivamente, y son responsables de la generación de potenciales postsinápticos excitatorios rápidos. Recientemente, ... -
Interacciones inhibidoras cruzadas entre los receptores Cys-Loop en neuronas mientéricas
(2007-07)"El ácido y-aminobutírico (G (GABA), la acetilcolina (ACh) y la serotonina (5-HT) son conocidos por jugar una función importante como neurotransmisores por abrir directamente los receptores ionotrópicos GABAA, nACh y 5-HT3 ... -
Interacción Dehidrina-Dehidrina: el caso de la OpsDHN1 de Opuntia streptacantha.
(2013)"Factores de estrés tales como la sequía, la salinidad y las bajas temperaturas provocan un déficit hídrico en las plantas, limitando la productividad de los cultivos a nivel mundial. Para hacer frente a dichas condiciones ... -
IPA-1 a Putative Chromatin Remodeler/Helicase-Related Protein of Trichoderma virens Plays Important Roles in Antibiosis Against Rhizoctonia solani and Induction of Arabidopsis Systemic Disease Resistance
(American Phytopathological Society, 2020)"Trichoderma spp. are filamentous fungi that colonize plant roots conferring beneficial effects to plants, either indirectly through the induction of their defense systems or directly through the suppression of phytopathogens ... -
IPI-SA3-C4, population of human preadipose cells with multipotent differentiation capability. Characterization as a model system for in vitro adipogenesis and optimization of its culture conditions
(2020-07)"The most commonly in vitro model systems used for adipose tissue studies are murine cell lines, which have genetic and metabolic differences with the human adipocytes. To date, there is not a general in vitro model to ... -
Isolation and characterization of mercury resistant trichoderma strains from soil with high levels of mercury and its effects on Arabidopsis thaliana mercury uptake
(Scientific Research Publishing Inc, 2018)"Traditional mining activities are usually correlated with high levels of soil pollution, which is a major environmental concern. Extensive mining activities have taken place in the San Joaquin region in the State of ... -
Isolation and phylogenetic classification of culturable psychrophilic prokaryotes from the Collins glacier in the Antarctica
(2011-05)"Culturable psychrophilic prokaryotes were obtained of samples of glacier sediment, seaside mud, glacier melted ice, and Deschampsia antarctica rhizosphere from Collins glacier, Antarctica. The taxonomic classification was ... -
La expresión neonatal de microRNAs como potenciales biomarcadores tempranos del síndrome metabólico
(2015)"El síndrome metabólico es un trastorno caracterizado por obesidad, hipertensión arterial, hipercolesterolemia, hiperlipidemia y alteraciones en el metabolismo de la glucosa, y constituye un factor de riesgo para el ... -
La melatonina inhibe el efecto estimulante de la acetilcolina sobre las neuronas sensoriales primarias del intestino del ratón.
(2012)"Esta hormona disminuye el dolor en la colitis ulcerativa, en el síndrome del intestino irritable y durante las erosiones hemorrágicas gástricas inducidas por el estrés, sugiriendo que podría estar modulando las funciones ... -
La sobreexpresión de AtGRDP2, una nueva proteína con un dominio rico en glicinas, acelera el crecimiento de las plantas y mejora la tolerancia al estrés
(2015)"Más del 20% de las tierras de cultivo en el mundo están afectadas por el estrés salino. Niveles tóxicos de sal en la planta reducen la capacidad para captar el agua provocando una rápida reducción en la tasa de crecimiento. ... -
La sobreexpresión de los Genes Id es un marcador de progresión del cáncer cervocouterino.
(2005)"Los genes Id codifican factores de transcripción que actúan como inhibidores de la diferenciación y promueven la proliferación celular, y su sobreexpresión se ha documentado en diversos tipos de cáncer. Id1 ha sido ... -
Lack of mutant huntingtin in cortical efferents improves behavioral inflexibility and corticostriatal dynamics in Huntington´s disease mice
(The American Physiological Society., 2019)"Abnormal communication between cerebral cortex and striatum plays a major role in the motor symptoms of Huntington’s disease (HD), a neurodegenerative disorder caused by a mutation of the huntingtin gene (mHTT). Because ... -
Las proteÍnas de silenciamiento Sir2-4, Ku70, Ku80 y Rif1 regulan negativamente la expresión de locus MTL3 de Candida glabrata.
(2010)"Candida glabrata es una levadura patógena oportunista relacionada filogenéticamente con Saccharomyces cerevisiae. Aunque en C. glabrata no se ha encontrado un ciclo de reproducción sexual, contiene tres loci similares a ...