Feedback induction of limit cycle in a bioreactor: controlling towards scale-down

Abstract

"The feedback stabilization of periodic orbits (induction of limit cycle) via PI-like control is proposed as plausible tool for scale-down studies. An isothermal continuous stirred tank bioreactor (CSTB), with nonideal mixing, is studied. Kinetics is assumed to be governed by Haldane law. The Ready-to-use equations for selecting the control gains are given. Thus, osccilatory behavior with arbitrary frequency and amplitude can be induced into the PI-controlled CSTB."